There are several possible causes of bladder wall calcification including cystitis (inflammation of the bladder), radiation to the area, schistosomiasis (a disease caused by parasitic worms that live in infested water located in tropical and subtropical regions), tuberculosis, and neoplasia (cancerous or non-cancerous growth). A diagnosis can usually be obtained from a combination of history, clinical examination, appropriate laboratory studies, and imaging of the bladder calcification and remaining urinary tract.