The gallbladder is a small, pear-shaped organ on the right side of the abdomen, just beneath the liver. Gallbladder wall thickening is a radiological term that is used to describe abnormal thickening of the gallbladder wall. Thickening of the gallbladder wall is a nonspecific finding (meaning it is difficult to say what caused it). It may occur as the result of various underlying conditions including chronic irritation and inflammation of the gallbladder (i.e. chronic cholecystitis), noncancerous conditions (e.g. hepatitis, pancreatitis, heart failure, renal failure), and gallbladder cancer.