March 16, 2026
Read
March 16, 2026

Enlarged Spleen: Diagnosis

Reviewed By:
Woman smiling with white magnifying circles highlighting skin texture on left side

Contents

Table of contents placeholder

The spleenโ€™s primary function is to filter the blood; it identifies and gets rid of old, misformed, or flawed red blood cells. A number of conditions, such as liver disease, some cancers, and infections, can cause splenomegaly, or an enlarged spleen. Itโ€™s typically asymptomatic, making it difficult to diagnose on its own.

According to the Mayo Clinic, in adults, splenomegaly is often found in the midst of a routine physical exam, as doctors can usually feel an enlarged spleen.

Your physician may, however, choose from a few methods to confirm a splenomegaly diagnosis:

  • MRIs: MRIs can trace the flow of blood through the spleen.
  • Blood tests: blood tests as simple as complete blood counts can assess the number of red blood cells, platelets, and white blood cells in your system to assess your spleenโ€™s functionality.
  • Ultrasounds or CT scans: these tests can aid in determining your spleenโ€™s size, and whether or not itโ€™s crowded your other organs.

Some of the Ezra MRIs could catch splenomegaly; you can learn more about our screening plans here.

Understand your risk for cancer with our 5 minute quiz.

Our scan is designed to detect potential cancer early.