LEARN ABOUT CT

CT vs. Ultrasound: Key Differences, Uses, and Benefits Explained

Discover the differences between CT scans and Ultrasounds. Learn their uses, benefits, and when to choose each for accurate medical diagnosis.

Introduction

Diagnostic imaging plays a crucial role in modern medicine. It allows healthcare providers to visualize the internal structures of the body for accurate diagnosis and treatment planning. It enables early detection of medical conditions, reduces the need for invasive exploratory procedures, and improves patient outcomes.

Both computed tomography (CT) and ultrasound are powerful diagnostic imaging techniques with distinct capabilities, applications, and limitations in modern medicine. Comparing these two methods provides valuable insights into their respective strengths, helping patients understand when and why each modality might be preferred in specific clinical scenarios.

CT Scans

A CT scan is a diagnostic imaging technique that utilizes X-rays and computer algorithms to generate detailed cross-sectional images of the body. It provides more precise and comprehensive visuals than standard X-rays, enabling healthcare providers to examine internal structures like bones, muscles, organs, and blood vessels. 

The technology behind CT scans involves a rotating X-ray source and detectors that capture the attenuation of X-rays as they pass through various tissues1. These measurements are processed using advanced tomographic reconstruction techniques to produce virtual slices of the body for detailed analysis. 

A CT scanner includes a motorized table that moves the patient through a circular device known as a gantry2. Within the gantry, the X-ray source and detectors rotate around the patient, often completing a full rotation in under a second. The detectors capture X-ray data from multiple angles, and a computer processes this data to construct cross-sectional images of internal structures.

Key Applications of CT Scans

Skeletal Imaging

CT scans provide high-resolution images of the skeletal system, making them invaluable for3:

  • Identifying bone fractures.
  • Detecting bone tumors.
  • Assessing abnormalities in bone structure. 

Acute Hemorrhage Detection

In cases of suspected internal bleeding, CT scans are the diagnostic tool of choice due to their rapid imaging capabilities4. They:

  • Quickly identify active bleeding in trauma or stroke scenarios.
  • Highlight bleeding sites and vascular origins through CT angiography.
  • Detect bleeding at rates as low as 0.3 mL/min.

Thoracic Imaging

CT scans are highly effective for examining the lungs and chest, offering detailed imaging for5:

  • Diagnosing and monitoring lung conditions like pneumonia, emphysema, and cancer.
  • Detecting lung nodules and other pulmonary abnormalities.

Oncological Uses

CT scans are critical in cancer diagnosis and treatment, particularly for6:

  • Diagnosing cancer, including lung cancer.
  • Providing detailed information about tumor size, location, and possible metastasis.
  • Assisting in treatment planning and monitoring disease progression.

Additionally, CT scans are important for evaluating gastrointestinal bleeding. Techniques such as CT angiography and multiphase CT enterography are especially effective for diagnosing both active bleeding and other bowel conditions7,8.

A medical practitioner putting a patient in for a CT scan.

Ultrasounds

An ultrasound, or sonography, is a non-invasive diagnostic imaging technique that uses high-frequency sound waves to create real-time images of internal body structures9. This medical procedure allows healthcare providers to visualize organs, tissues, and blood flow without the need for invasive methods or radiation exposure. 

The technology behind ultrasound imaging relies on the principle of sound wave reflection. A small handheld device called a transducer or probe emits high-frequency sound waves into the body. These sound waves, inaudible to the human ear, bounce off different tissues and structures within the body. The transducer then captures the returning echoes, which are processed by a computer to generate detailed images displayed on a monitor10

A medical practitioner showing a woman her ultrasound results.

Key Applications of Ultrasound

Ultrasound has a wide range of applications in medical diagnostics and monitoring:

Pregnancy Monitoring: Ultrasound is routinely used to assess fetal development, check for abnormalities, determine gestational age, and guide prenatal procedures11

Organ Examination: It helps visualize and evaluate internal organs such as the liver, gallbladder, pancreas, kidneys, and thyroid gland12.

Cardiovascular Assessment: Doppler ultrasound can examine blood flow and heart function and detect vascular abnormalities13.

Musculoskeletal Imaging: Ultrasound is useful for examining muscles, tendons, and joints14.

Cancer Detection: It aids in differentiating between solid tumors and fluid-filled cysts and can detect tumors and lesions with 80-90% accuracy15,16.

Procedural Guidance: Ultrasound helps guide minimally invasive procedures, like needle biopsies and fluid aspiration17.

Pediatric Care: It is particularly valuable for imaging the brain, spine, and hips in infants18.

What Are The Key Differences Between CT and Ultrasound?

Imaging Techniques

As mentioned above, CT scans use X-ray technology combined with computer processing to create detailed cross-sectional images of the body. In contrast, ultrasound employs high-frequency sound waves to produce real-time images of internal structures.

Accuracy and Detail

CT scans generally provide higher resolution and more detailed images compared to ultrasounds. They excel at visualizing bone, soft tissue, and blood vessels, offering a comprehensive view of the body’s internal structures. CT scans are particularly effective at detecting small abnormalities - like nodules in lung cancer - making them useful for diagnosing conditions like cancer and heart disease19.

While ultrasounds produce lower-resolution images, they offer real-time visualization of organ function and tissue movement. They are effective at evaluating soft tissue, monitoring pregnancy, and guiding procedures. Ultrasounds are also more effective at imaging superficial structures and are often the first choice for examining areas that can be felt through the skin20.

An ultrasound image of a fetus.

Safety Considerations

A key difference between the two methods lies in their safety profiles. CT scans expose patients to ionizing radiation, which poses a small but cumulative risk, especially with multiple scans21. The radiation exposure from a single CT scan is comparable to about three years of background radiation.

For this reason, Ezra uses low-dose CT (LDCT) in their Full-Body Plus scans, reducing radiation exposure and improving safety.

Ultrasound uses no ionizing radiation, making it safer for all patients, including pregnant women and children.

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What Are the Benefits and Limitations of CT and Ultrasound?

CT Scans

Benefits: CT scans offer unparalleled detail, particularly for bony structures, lung abnormalities, and complex internal injuries22. They excel in detecting fractures, tumors, hemorrhages, and cancers. Rapid imaging makes them indispensable in emergency settings, such as assessing trauma or stroke. CT angiography adds precision in evaluating vascular issues, including active bleeding and blood flow23.

Limitations: The procedure involves ionizing radiation exposure, making it less ideal for children or pregnant individuals24. High costs and limited portability restrict accessibility. Contrast agents used in some scans can pose a risk for individuals with allergies or kidney impairment25

Ultrasounds

Benefits: Ultrasounds are safe, non-invasive, and do not use ionizing radiation, making them ideal for pregnant patients and repetitive imaging needs. They are cost-effective, portable, and excellent for visualizing soft tissues, fluid collections, and blood flow26. Common uses include evaluating pregnancies, abdominal organs, and superficial tissues.

Limitations: Ultrasounds are less effective for imaging air-filled or dense structures, such as the lungs or bones12. Image quality can vary based on operator skill and patient body habitus, and they lack the comprehensive detail of CT scans.

When Should I Get a CT Instead of an Ultrasound?

CT scans are typically chosen over ultrasound in the following cases:

  • Diagnosing appendicitis in adults, with CT showing higher sensitivity (94 percent vs. 76 percent for ultrasound)27.
  • Evaluating diverticulitis, where CT has a higher sensitivity (81 percent vs. 61 percent for ultrasound)28.
  • Assessing urgent gynecological disorders, with CT demonstrating higher sensitivity (67 percent vs. 37 percent for ultrasound).
  • Examining bones, blood vessels, and soft tissues22.
  • Guiding biopsies and other procedures such as abscess drainages and minimally invasive tumor treatments29,30
  • Planning for and assessing the results of surgery, such as organ transplants31.
  • Staging, planning, and administrating radiation treatments for tumors.
  • Emergency cases where internal injuries and bleeding need to be quickly identified.

CT scans are preferred in these situations due to their ability to provide more detailed images, detect diseases at earlier stages, and offer a comprehensive view of the entire body. However, it should be noted that CT scans do involve radiation exposure and are generally more expensive than ultrasound.

Frequently Asked Questions

Why would you need an ultrasound after a CT scan?

There are several reasons why an ultrasound might be performed after a CT scan:

  1. Follow-up imaging: Ultrasound is often preferred for follow-up imaging to reduce radiation exposure, particularly when frequent scans are needed. This is especially important for conditions like ectatic abdominal aorta or pancreatitis32.
  2. Radiation concerns: In cases where minimizing radiation exposure is crucial, such as in pregnant patients or children, ultrasound may be preferred for additional imaging needs.
  3. Real-time imaging: Ultrasound provides real-time imaging, which can be beneficial for assessing dynamic processes or structures that may have changed since the CT scan.

Is a CT scan better than ultrasound?

CT scans and ultrasounds each have their own strengths and are better suited for different diagnostic purposes. Neither is universally “better” than the other, as their effectiveness depends on the specific medical situation. For example, CT scans can detect small abnormalities and are better at screening for certain types of tumors, whereas ultrasound does not use ionizing radiation, making it safer for frequent use.

Conclusion

Both CT and ultrasounds are indispensable diagnostic tools, each with unique strengths and limitations. CT scans provide detailed, high-resolution images, whereas ultrasound offers safe, real-time imaging. Choosing the right method depends on the medical context, the condition investigated, and the patient’s specific needs. 

If you want to be proactive about your health, why not book an Ezra Full-Body Plus? We combine MRI with LDCT to catch potential cancer earlier, leveraging AI through the screening process to make it more efficient, affordable, and faster.

References

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2. Computed Tomography (CT). National Institute of Biomedical Imaging and Bioengineering. Accessed December 9, 2024. https://www.nibib.nih.gov/science-education/science-topics/computed-tomography-ct

3. Computed Tomography (CT). National Institute of Biomedical Imaging and Bioengineering. Accessed December 9, 2024. https://www.nibib.nih.gov/science-education/science-topics/computed-tomography-ct

4. Kamal H, Lopez V, Sheth SA. Machine Learning in Acute Ischemic Stroke Neuroimaging. Front Neurol. 2018;9:945. doi:10.3389/fneur.2018.00945

5. Bhalla AS, Das A, Naranje P, Irodi A, Raj V, Goyal A. Imaging protocols for CT chest: A recommendation. Indian J Radiol Imaging. 2019;29(3):236-246. doi:10.4103/ijri.IJRI_34_19

6. Computed Tomography (CT) Scans and Cancer Fact Sheet - NCI. January 3, 2024. Accessed July 16, 2024. https://www.cancer.gov/about-cancer/diagnosis-staging/ct-scans-fact-sheet

7. Wortman JR, Landman W, Fulwadhva UP, Viscomi SG, Sodickson AD. CT angiography for acute gastrointestinal bleeding: what the radiologist needs to know. Br J Radiol. 90(1075):20170076. doi:10.1259/bjr.20170076

8. Ilangovan R, Burling D, George A, Gupta A, Marshall M, Taylor SA. CT enterography: review of technique and practical tips. Br J Radiol. 2012;85(1015):876-886. doi:10.1259/bjr/27973476

9. Ultrasound scan. nhs.uk. October 18, 2017. Accessed December 9, 2024. https://www.nhs.uk/conditions/ultrasound-scan/

10. Ultrasound. National Institute of Biomedical Imaging and Bioengineering. Accessed December 10, 2024. https://www.nibib.nih.gov/science-education/science-topics/ultrasound

11. Ulrich CC, Dewald O. Pregnancy Ultrasound Evaluation. In: StatPearls. StatPearls Publishing; 2024. Accessed December 10, 2024. http://www.ncbi.nlm.nih.gov/books/NBK557572/

12. Radiology (ACR) RS of NA (RSNA) and AC of. Ultrasound - Abdomen. Radiologyinfo.org. Accessed December 10, 2024. https://www.radiologyinfo.org/en/info/abdominus

13. Doppler ultrasound. Heart and Stroke Foundation of Canada. Accessed December 10, 2024. https://www.heartandstroke.ca/en/heart-disease/tests/doppler-ultrasound/

14. Radiology (ACR) RS of NA (RSNA) and AC of. Ultrasound - Musculoskeletal. Radiologyinfo.org. Accessed December 10, 2024. https://www.radiologyinfo.org/en/info/musculous

15. Vibhakar AM, Cassels JA, Botchu R, Rennie WJ, Shah A. Imaging update on soft tissue sarcoma. J Clin Orthop Trauma. 2021;22:101568. doi:10.1016/j.jcot.2021.101568

16. Soft tissue sarcoma ultrasound: What to expect. May 23, 2023. Accessed December 10, 2024. https://www.medicalnewstoday.com/articles/soft-tissue-sarcoma-ultrasound

17. Ultrasound guided fine needle aspiration or biopsy. Newcastle Hospitals NHS Foundation Trust. March 17, 2022. Accessed December 10, 2024. https://www.newcastle-hospitals.nhs.uk/services/radiology/ultrasound/ultrasound-guided-fine-needle-aspiration-or-biopsy/

18. Kang YR, Koo J. Ultrasonography of the pediatric hip and spine. Ultrasonography. 2017;36(3):239-251. doi:10.14366/usg.16051

19. Radiology (ACR) RS of NA (RSNA) and AC of. Chest CT. Radiologyinfo.org. Accessed December 9, 2024. https://www.radiologyinfo.org/en/info/chestct

20. Catalano O, Varelli C, Sbordone C, et al. A bump: what to do next? Ultrasound imaging of superficial soft-tissue palpable lesions. J Ultrasound. 2019;23(3):287-300. doi:10.1007/s40477-019-00415-z

21. Gargani L, Picano E. The risk of cumulative radiation exposure in chest imaging and the advantage of bedside ultrasound. Crit Ultrasound J. 2015;7:4. doi:10.1186/s13089-015-0020-x

22. Radiology (ACR) RS of NA (RSNA) and AC of. Body CT. Radiologyinfo.org. Accessed December 9, 2024. https://www.radiologyinfo.org/en/info/bodyct

23. Radiology (ACR) RS of NA (RSNA) and AC of. CT Angiography (CTA). Radiologyinfo.org. Accessed December 9, 2024. https://www.radiologyinfo.org/en/info/angioct

24. Health C for D and R. What are the Radiation Risks from CT? FDA. Published online March 11, 2018. Accessed December 9, 2024. https://www.fda.gov/radiation-emitting-products/medical-x-ray-imaging/what-are-radiation-risks-ct

25. Hermena S, Young M. CT-scan Image Production Procedures. In: StatPearls. StatPearls Publishing; 2024. Accessed December 9, 2024. http://www.ncbi.nlm.nih.gov/books/NBK574548/

26. Wang S, Hossack JA, Klibanov AL. From Anatomy to Functional and Molecular Biomarker Imaging, and Therapy: Ultrasound is Safe, Ultrafast, Portable, and Inexpensive. Invest Radiol. 2020;55(9):559-572. doi:10.1097/RLI.0000000000000675

27. Reich B, Zalut T, Weiner SG. An international evaluation of ultrasound vs. computed tomography in the diagnosis of appendicitis. International Journal of Emergency Medicine. 2011;4(1):68. doi:10.1186/1865-1380-4-68

28. van Randen A, Laméris W, van Es HW, et al. A comparison of the Accuracy of Ultrasound and Computed Tomography in common diagnoses causing acute abdominal pain. Eur Radiol. 2011;21(7):1535-1545. doi:10.1007/s00330-011-2087-5

29. Khosla R, McLean AW, Smith JA. Ultrasound-guided versus computed tomography-scan guided biopsy of pleural-based lung lesions. Lung India. 2016;33(5):487-492. doi:10.4103/0970-2113.188961

30. Clark RA, Towbin R. Abscess drainage with CT and ultrasound guidance. Radiol Clin North Am. 1983;21(3):445-459.

31. Radiology (ACR) RS of NA (RSNA) and AC of. Computed Tomography (CT) - Abdomen and Pelvis. Radiologyinfo.org. Accessed December 9, 2024. https://www.radiologyinfo.org/en/info/abdominct

32. Caraiani C, Yi D, Petresc B, Dietrich C. Indications for abdominal imaging: When and what to choose? J Ultrason. 2020;20(80):e43-e54. doi:10.15557/JoU.2020.0008