LEARN ABOUT MRI

MRI for Bone Cancer Detection

Bone cancer can be a serious and potentially life-threatening condition. Therefore, early detection is crucial for catching these cancers early and treating them effectively. In this article, explore the uses, procedures, and costs of MRI screening for bone cancer.

Introduction

Magnetic Resonance Imaging (MRI) is a sophisticated technology that is excellent for detecting bone cancers due to its superior soft tissue contrast and ability to visualize bone marrow abnormalities before structural changes occur in the bone. Its high sensitivity (91-95 percent) and specificity (95-97 percent) for detecting bone tumors, combined with the capability to delineate tumor extent and relation to surrounding structures, make MRI the imaging method of choice for comprehensive evaluation of primary bone cancers and metastases1,2.

What is MRI and How Does it Work?

Magnetic Resonance Imaging (MRI) is a non-invasive imaging method that uses strong magnets and radiofrequency waves to produce high-resolution cross-sectional images of soft tissues, organs, and internal structures3. The process works by aligning the hydrogen atoms in the body with the MRI machine’s magnetic field, after which radiofrequency pulses disrupt this alignment. Once the pulses are turned off, the atoms return to their original position, emitting signals that are used to generate detailed images4. Unlike X-rays and CT scans, MRI does not involve ionizing radiation, making it a safer choice for repeated imaging.

Importance of MRI in Detecting Bone Cancer

MRI is crucial for early bone cancer detection due to its superior soft tissue contrast and ability to visualize bone marrow. It can differentiate benign from malignant tumors based on size, depth, enhancement patterns, and other characteristics5.

Advantages of MRI for Bone Cancer Detection

MRI offers several key advantages for detecting bone cancer.

Non-Invasive Nature

MRI is non-invasive and uses no ionizing radiation. This makes it safe for repeated use in monitoring patients and is especially beneficial for those requiring frequent follow-ups.

High-Resolution Imaging

MRI provides superior soft tissue contrast and high spatial resolution, allowing for detailed visualization of bone marrow spaces and surrounding structures6. It can reveal metastases in bone marrow before any changes in internal bone structure occur.

Early Detection Capability

MRI can also detect bone metastases very early, often before they are visible on other imaging modalities7:

  • Some types of bone metastases can be detected by MRI even before they grow large enough for radiotracers to pick up8.
  • MRI’s sensitivity for detecting bone metastases ranges from 95-100 percent, surpassing other common techniques1.

MRI Procedure for Bone Cancer

The procedure for an MRI is very straightforward. However, there are general rules to follow9.

Before: Leave your jewelry at home. You can eat and drink as usual, but avoid foods that cause bloating as they can impact image quality. If your MRI procedure will involve contrast agents or sedatives, avoid eating or drinking for four hours beforehand to reduce nausea and vomiting risks. There are no restrictions on sexual activity beforehand. A radiologist will talk you through the procedure beforehand.

During: You will be asked to lie on a table inside the machine, which makes loud noises. Earbuds or music may be provided to make you more comfortable. The scan typically lasts 30-60 minutes. While it can be difficult to stay still for this long, it’s best to stay as still as possible to avoid delays. If any issues should arise, you will be able to communicate with the radiologist via an intercom.

After: Within roughly a week of the scan, you will be contacted by a medical practitioner working with Ezra. On the day of the appointment, you will receive a copy of your report and access to your scanned images through the online portal.

For more information on how to prepare for an MRI, you can read this article here.

Photo Of A Doctor Examining Patient

Comparing MRI with Other Imaging Techniques

Bone Scan vs. MRI for Cancer

While bone scans use radioactive tracers to identify areas of increased bone activity, which can indicate cancer, MRI provides more detailed images of bone and surrounding soft tissues10. Furthermore, MRI is generally more sensitive for detecting early bone metastases and can often find smaller lesions than bone scans11.

Pros and Cons for Bone Cancer Detection

MRI 

Pros: 

  • Excellent soft tissue contrast
  • No radiation exposure
  • Can detect early bone marrow involvement

Cons: 

  • Longer scan times
  • More expensive
  • Not suitable for patients with certain metal implants

CT Scans

Pros: 

  • Faster scan times
  • Good for detecting bone destruction
  • Widely available

 Cons: 

  • Exposes patients to radiation
  • Less effective for early detection of bone marrow involvement

X-rays

Pros: 

  • Widely available and inexpensive
  • Quick to perform

Cons:

  • Limited detection  of early-stage bone cancer
  • May miss small lesions
  • Exposes patients to radiation
Two medical practitioners observing an MRI taking place.

FAQs About MRI for Bone Cancer Detection

Can an MRI scan be used for hip and leg bones?

Yes, MRI can be used to scan hip and leg bones12. It’s particularly useful for:

  1. Detecting bone marrow abnormalities
  2. Evaluating soft tissue structures around bones
  3. Identifying early stages of avascular necrosis in the hip
  4. Assessing joint problems in the hip and knee

What is the Cost of a bone MRI?

MRI costs vary depending on factors like scan type, facility, location, and insurance coverage. Hospital-based MRIs are generally more expensive than those at independent imaging centers. Patients can save money by comparing prices, exploring cash payment discounts, and utilizing insurance benefits or financial assistance programs. 

At Ezra, you can get a full-body MRI for the all-inclusive price of $2395. This is a 60-minute MRI, after which you will be provided with a medical practitioner to help you understand your results.

Summary: Cancer Detection in the Bone

MRI is vital for detecting bone cancer, offering superior imaging resolution without radiation. It excels at identifying early bone metastases and bone marrow involvement, making it crucial for timely diagnosis. Preparation includes following specific guidelines, such as removing metal objects and staying still during the scan to ensure optimal image quality. MRI compares favorably to other imaging techniques like bone and CT scans, providing better soft tissue contrast. 

Ready to be proactive with your health? Book an Ezra full-body MRI today to detect any issues early and put you on the road to long-term health. Our yearly scan screens for potential cancers early, using AI to enhance the process, making it more efficient and affordable.

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 References

1. O’Sullivan GJ, Carty FL, Cronin CG. Imaging of bone metastasis: An update. World J Radiol. 2015;7(8):202-211. doi:10.4329/wjr.v7.i8.202

2. Aisen AM, Martel W, Braunstein EM, McMillin KI, Phillips WA, Kling TF. MRI and CT evaluation of primary bone and soft-tissue tumors. AJR Am J Roentgenol. 1986;146(4):749-756. doi:10.2214/ajr.146.4.749

3. MRI - Mayo Clinic. Accessed January 29, 2025. https://www.mayoclinic.org/tests-procedures/mri/about/pac-20384768

4. Berger A. Magnetic resonance imaging. BMJ. 2002;324(7328):35.

5. Chung WJ, Chung HW, Shin MJ, et al. MRI to differentiate benign from malignant soft-tissue tumours of the extremities: a simplified systematic imaging approach using depth, size and heterogeneity of signal intensity. Br J Radiol. 2012;85(1018):e831-e836. doi:10.1259/bjr/27487871

6. Wu Y, Li D, Xing L, Gold G. Deriving new soft tissue contrasts from conventional MR images using deep learning. Magnetic Resonance Imaging. 2020;74:121-127. doi:10.1016/j.mri.2020.09.014

7. Sanal SM, Flickinger FW, Caudell MJ, Sherry RM. Detection of bone marrow involvement in breast cancer with magnetic resonance imaging. J Clin Oncol. 1994;12(7):1415-1421. doi:10.1200/JCO.1994.12.7.1415

8. Nakanishi K, Tanaka J, Nakaya Y, et al. Whole-body MRI: detecting bone metastases from prostate cancer. Jpn J Radiol. 2022;40(3):229-244. doi:10.1007/s11604-021-01205-6

9. MRI scan - How it’s performed. nhs.uk. September 5, 2018. Accessed March 14, 2025. https://www.nhs.uk/conditions/mri-scan/what-happens/

10. Vaz S, Usmani S, Gnanasegaran G, Van den Wyngaert T. Molecular imaging of bone metastases using bone targeted tracers. Q J Nucl Med Mol Imaging. 2019;63(2):112-128. doi:10.23736/S1824-4785.19.03198-4

11. Lecouvet FE, Simon M, Tombal B, Jamart J, Vande Berg BC, Simoni P. Whole-body MRI (WB-MRI) versus axial skeleton MRI (AS-MRI) to detect and measure bone metastases in prostate cancer (PCa). Eur Radiol. 2010;20(12):2973-2982. doi:10.1007/s00330-010-1879-3

12. Radiology (ACR) RS of NA (RSNA) and AC of. Hip MRI. Radiologyinfo.org. Accessed March 14, 2025. https://www.radiologyinfo.org/en/info/mri-hip